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KMID : 0363219960340040697
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Korean Journal of Dermatology
1996 Volume.34 No. 4 p.697 ~ p.704
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A Case of Type IV Hyperlipoproteinemia with Xanthoma Tuberosum and Xanthoma Eruptivum
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Abstract
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We report a case of type IV hyperlipoproteinemia associated with xdanthoma tuberosum and xanthoma eruptivum, which improved by treatment with gemfibrozil and procetofene. A 460year-old male patient visited our clinic for evaluation of evaluation
of
multiple orange-yellow colored nodules on the elbows and multiple papules on the knees, buttocks and back. Laboratory examination sowed an abnormal elevation of serum cholesterol and triglyceride. Lipoprotein electrophoresis showed an increase of
pre-βband and plasma standing test showed turbid plasma. Analysis of lipoprotein revealed increase of VLDL level in his plasma. The biopsy specimens from the nodule on the elbow and the papule on the back r4vealed characteristic findings of
xanthoma.
We diagnosed the patient as type IV hyperlipoproteinemia. After 5 months of treatment with diet restriction, gemfibrozil, and procetofene, the serum levels of cholesterol and triglyceride were reduced to normal level. The skin lesions of the both
back
and buttock showed marked improvement and the skin lesions on the elbows and knee were much improved.
(Kor J Dermatol 1996;34(4) : 697~702)
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